Table 1.
Genotypic and phenotypic characteristics of large and SCs of clinical M. tuberculosis strains
| Strain | embB | inhA | rpoB | rpoC | gyrA | gyrB | glpK | Colony size |
| TDR193-SC | Met306Val; Met423Thr | Ile194Thr | Ser531Leu | Ala542Ala | Glu21Gln; Ser95Thr; Gly668Asp | Val340Leu | Ins573C (7C → 8C) (frameshift) | Small |
| TDR193-LC | Met306Val; Met423Thr | Ile194Thr | Ser531Leu | Ala542Ala; Val775Ala | Glu21Gln; Ser95Thr; Gly668Asp | Val340Leu | WT (7C) | Large |
| TDR193-SC-RevLC1 | Met306Val; Met423Thr | Ile194Thr | Ser531Leu | Ala542Ala | Glu21Gln; Ser95Thr; Gly668Asp | Val340Leu | Ins573CCC (7C → 10C) (Gly192 insertion) | Large |
| TDR193-SC-RevLC9 | Met306Val; Met423Thr | Ile194Thr | Ser531Leu | Ala542Ala | Glu21Gln; Ser95Thr; Gly668Asp | Val340Leu | WT (7C) | Large |
| C71-SC | Ala630Val | WT | WT | WT | Glu21Gln | WT | Ins573CCCC (66%)/Ins573CCC (34%) (7C → 11C/10C) (Mix of frameshift and Gly192 insertion) | Small and Large |
| C71-LC | Ala630Val | WT | WT | WT | Glu21Gln | WT | Ins573CCC (7C → 10C) (Gly192 insertion) | Large |
| C71-SC- RevLC | Ala630Val | WT | WT | WT | Glu21Gln | WT | Ins573CCC (7C → 10C) (Gly192 insertion) | Large |