Table 1.
Broad characterization of A. actinomycetemcomitans and all coinfection species
| Species | Strain | Habitat | Description | Genome size (Mbp) | Protein coding genes | Protein coding genes with EC number | In vivo essential genes |
| Aggregatibacter actinomycetemcomitans | 624 | Oral | Facultative anaerobe | 2.37 | 2,283 | 740 | 199 |
| Actinomyces israelii | F0345 | Oral | Obligate anaerobe | 4.02 | 3,346 | 808 | 370 |
| Actinomyces oris | MG-1 | Oral | Facultative anaerobe | 2.93 | 2,704 | 578 | 207 |
| Campylobacter rectus | 33238 | Oral | Microaerophile | 2.51 | 2,971 | 560 | 283 |
| Candida albicans | SC5314 | Oral | Facultative anaerobe | 14.28 | 6,030 | 1,402 | 182 |
| Filifactor alocis | 35896 | Oral | Obligate anaerobe | 1.93 | 1,641 | 446 | 308 |
| Fusobacterium nucleatum | 25586 | Oral | Obligate anaerobe | 2.17 | 2,067 | 612 | 238 |
| Lactobacillus reuteri | FJ1 | Oral | Aerotolerant anaerobe | 2.15 | 1,945 | 569 | 298 |
| Neisseria mucosa | C102 | Oral | Facultative anaerobe | 2.16 | 2,026 | 706 | 249 |
| Parvimonas micra | 33270 | Oral | Obligate anaerobe | 1.63 | 1,485 | 437 | 263 |
| Porphyromonas gingivalis | W83 | Oral | Obligate anaerobe | 2.34 | 1,909 | 534 | 363 |
| Prevotella intermedia | 25611 | Oral | Obligate anaerobe | 2.67 | 2,191 | 537 | 232 |
| Streptococcus gordonii | DL1.1 | Oral | Facultative anaerobe | 2.20 | 2,076 | 659 | 204 |
| Streptococcus intermedius | 27335 | Oral | Facultative anaerobe | 1.91 | 1,875 | 583 | 294 |
| Streptococcus mutans | UA159 | Oral | Facultative anaerobe | 2.03 | 1,960 | 627 | 193 |
| Streptococcus sanguinis | 10556 | Oral | Facultative anaerobe | 2.39 | 2,272 | 713 | 245 |
| Bacillus subtilis | PY79 | Nonoral | Facultative anaerobe | 4.03 | 4,138 | 1,129 | 257 |
| Burkholderia cenocepacia | J2315 | Nonoral | Obligate aerobe | 8.06 | 7,116 | 1,706 | 326 |
| Enterobacter cloacae | 13047 | Nonoral | Facultative anaerobe | 5.60 | 5,284 | 1,480 | 148 |
| Enterococcus faecalis | V583 | Nonoral | Facultative anaerobe | 3.22 | 3,266 | 789 | 266 |
| Escherichia coli | W3110 | Nonoral | Facultative anaerobe | 4.65 | 4,226 | 1,439 | 191 |
| Francisella sp. | W12-1067 | Nonoral | Obligate aerobe | 1.70 | 1,548 | 533 | 255 |
| Haemophilus influenzae | 86-028NP | Nonoral | Facultative anaerobe | 1.91 | 1,816 | 691 | 146 |
| Saccharomyces cerevisiae | BY4741 | Nonoral | Facultative anaerobe | 11.62 | 5,869 | 1,450 | 115 |
| Serratia marcescens | Db11 | Nonoral | Facultative anaerobe | 5.11 | 4,709 | 1,436 | 246 |
| Streptococcus pyogenes | 950771 | Nonoral | Facultative anaerobe | 1.84 | 1,771 | 584 | 256 |