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. 2019 Sep 23;12:7809–7821. doi: 10.2147/OTT.S212596

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© 2019 Zhou et al.

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Results of the micro-PET analysis of the combined effect of SB431542 and RFA on subcutaneous growth of BC cells. A patient-derived BC cell line (patient no. 1) was injected into nude mice to form subcutaneous tumors. RFA of the tumor tissues was performed, and the mice were treated with SB431542 at a dose of 1 mg/kg via oral administration. The results of micro-PET at particular time points, showing (A) images of micro-PET, (B) tumor areas and (C) tumor intensity. In the micro-PET images, the arrows indicate the location of the tumor tissues (A). *P<0.05 versus control group with RFA treatment group; ^#P<0.05 versus RFA treatment group with RFA+SB431542 treatment group.

Abbreviations: BC, bladder cancer; qPCR, quantitative real-time polymerase chain reaction; RFA, radiofrequency ablation; PET, positron emission computed tomography.