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. 2019 Sep 23;14:7759–7780. doi: 10.2147/IJN.S221433

Figure 8.

Figure 8

(A) Surface modified UCNPs with organic dyes doped within silicon to get single emission from NPs. Antibody conjugation of these modified nanoparticles creates influential probes for multiplexed in situ molecular mapping of tumor biomarkers. Reproduced with permission from Zhou L, Wang R, Yao C, et al. Single-band upconversion nanoprobes for multiplexed simultaneous in situ molecular mapping of cancer biomarkers. Nat Commun. 2015;6:6938.172 Copyright Springer Nature 2015. (B) Schematic representation of prodrug activation using NIR and intracellular apoptosis by UCL. Reproduced with permission from Min Y, Li J, Liu F, Yeow EKL, Xing B. Near-infrared lightmediated photoactivation of a platinum antitumor prodrug and simultaneous cellular apoptosis imaging by upconversion-luminescent nanoparticles. Angew Chem Int Ed. 2014;53(4):1012–1016.173 Copyright 2013, John Wiley and Sons.