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TAK1、TAB1表达水平与食管癌患者临床病理参数的相关性分析

Correlations of TAB1 and TAK1 protein expressions and the clinicopathological parameters of the patients with esophageal cancer (n=84)

Clinicopathological parameters	TAK1 protein				TAB1 protein				Co-expression TAK1/TAB1
	Low	High	P		Low	High	P		No	Yes	P
*In accordance with staging of cancer of the esophagus and esophagogastric junction (pathologic TNM staging) for the eighth edition of the AJCC/UICC cancer staging manuals.
Gender			0.386				0.174				0.425
Male	14	32			25	21			27	19
Female	15	23			15	23			19	19
Age (year)			0.885				0.490				0.677
< 60	8	16			10	14			14	10
≥60	21	39			30	30			32	28
Tumor size			0.020				0.062				0.001
< 5 cm	25	34			32	27			39	20
≥5 cm	4	21			8	17			7	18
Location			0.750				0.708				0.989
Upper	4	7			6	5			6	5
Middle	15	33			21	27			26	22
Low	10	15			13	12			14	11
Invasion depth			0.005				0.012				0.035
pT 1	10	4			11	3			11	3
pT 2	7	24			16	15			19	12
pT 3	12	27			13	26			16	23
Lymph node metastasis			0.001				0.032				0.001
Positive	10	40			19	31			20	30
Negative	19	15			21	13			26	8
Differentiation			0.084				0.161				0.426
Poor	5	12			9	8			9	4
Moderate	16	38			22	32			27	27
Well	8	5			9	4			10	7
Clinical stage*			0.000				0.037				0.003
Ⅰ	9	2			9	2			10	1
Ⅱ	13	16			14	15			19	10
Ⅲ	7	37			17	27			17	27