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. 2018 Jul 20;38(7):818–823. [Article in Chinese] doi: 10.3969/j.issn.1673-4254.2018.07.08

2.

盐酸地尔硫卓对人肝癌7402细胞增殖的影响

Effect of diltiazem hydrochloride on proliferation of 7402 cells (n=3, Mean±SD)

7402 12 h 24 h 48 h
A570 IR(%) A570 IR(%) A570 IR(%)
*P < 0.05, **P < 0.01 comparied with the control group. IR: Inhibition ratio.
Control 0.522±1.155 0.404±0.220 0.546±0.075
25 μmol/L 0.120±0.169 0.77 0.882±0.418** -1.18 0.476±0.089 0.13
50 μmol/L 0.180±0.154 0.66 0.965±0.342** -1.39 0.551±0.166 -0.009
100 μmol/L 0.327±0.220 0.37 0.955±0.379** -1.36 0.475±0.076 0.130
200 μmol/L 0.285±0.135 0.45 1.009±0.174** -1.50 0.520±0.0600 0.057
400 μmol/L 0.067±0.111* 0.87 0.817±0.237* -1.02 0.510±0.078 0.07