2.
盐酸地尔硫卓对人肝癌7402细胞增殖的影响
Effect of diltiazem hydrochloride on proliferation of 7402 cells (n=3, Mean±SD)
| 7402 | 12 h | 24 h | 48 h | |||||
| A570 | IR(%) | A570 | IR(%) | A570 | IR(%) | |||
| *P < 0.05, **P < 0.01 comparied with the control group. IR: Inhibition ratio. | ||||||||
| Control | 0.522±1.155 | 0.404±0.220 | 0.546±0.075 | |||||
| 25 μmol/L | 0.120±0.169 | 0.77 | 0.882±0.418** | -1.18 | 0.476±0.089 | 0.13 | ||
| 50 μmol/L | 0.180±0.154 | 0.66 | 0.965±0.342** | -1.39 | 0.551±0.166 | -0.009 | ||
| 100 μmol/L | 0.327±0.220 | 0.37 | 0.955±0.379** | -1.36 | 0.475±0.076 | 0.130 | ||
| 200 μmol/L | 0.285±0.135 | 0.45 | 1.009±0.174** | -1.50 | 0.520±0.0600 | 0.057 | ||
| 400 μmol/L | 0.067±0.111* | 0.87 | 0.817±0.237* | -1.02 | 0.510±0.078 | 0.07 | ||