2.

SNP位点与产后抑郁的关联分析

Analysis of association between single nucleotide polymorphisms (SNP) and postpartum depression

SNP		Genotype	PPD	Non-PPD	Additive			Dominant			Recessive
					P	OR (95% CI)	P	OR (95% CI)	P		OR (95% CI)
*P < 0.05 vs control.
COMT		CC	42	234		Reference	0.707	0.912 (0.563-1.476)	0.010*		2.481 (1.214-5.072)
	rs2020917	CT	24	189	0.205	0.707 (0.414-1.210)
		TT	12	31	0.039*	2.157 (1.026-4.533)
		AA	43	239		Reference	0.726	0.918 (0.568-1.482)	0.014*		2.478 (1.179-5.210)
	rs737865	AG	25	190	0.245	0.731 (0.431-1.241)
		GG	11	28	0.043*	2.184(1.012-4.713)
		CC	44	251		Reference	0.958	0.987 (0.613-1.591)	0.940		1.033 (0.445-2.397)
	rs4633	CT	29	169	0.934	0.979 (0.589-1.626)
		TT	7	39	0.957	1.024 (1.431-2.434)
		AA	43	222		Reference	0.363	0.798 (0.490-1.298)	0597		1.228 (0.573-2.634)
	rs2075507	AG	25	177	0.243	0.729 (0.429-1.240)
		GG	9	43	0.847	1.081 (0.491-2.379)
		CC	18	85		Reference	0.414	0.787 (0.443-1.399)	0.473		1.199 (0.730-1.970)
	rs933271	CT	33	225	0.248	0.693 (0.370-1.295)
		TT	29	147	0.830	0.932 (0.488-1.777)
		TT	14	89		Reference	0.685	0.897 (0.472-1.637)	0.071		0.640 (0.393-1.042)
MAOA	rs6323	GT	33	227	0.818	1.082 (0.553-2.118)
		GG	33	142	0.258	0.677 (0.343-1.335)