6.

ETV4 knockdown lowers IER3 mRNA expression in HCC cells treated with sorafenib or cisplatin. A: SMMC-7721 cells were treated with DMSO, sorafenib (5 μmol/L) or cisplatin (5μmol/L) for 48 h after transfection with si-ETV4 for 24 h. Data were analyzed using One-way ANOVA, and the error bars indicate SD. *P < 0.05, **P < 0.01, ***P < 0.0001. B: TCGA database was used to analyze the mRNA correlation between IER3 and ETV4. The data were analyzed using Pearson's correlation analysis (n=351, P < 0.0001, r=0.3061)