2.
结核病例组与对照组的HLA-A等位基因频率比较
Frequencies of HLA-A alleles in active tuberculosis group and control group
| HLA-A | APTB (n=294) | Control (n=644) | χ2 | OR (95% CI) | P | Pc | |||
| Positive (n) | GF (%) | Positive (n) | GF (%) | ||||||
| GF: Gene frequency; OR: Odds ratio; CI: Confidence interval; Pc: P value after Bonferroni correction. | |||||||||
| 1101 | 191 | 2.5 | 367 | 28.5 | 3.074 | 1.207 (0.978-1.491) | 0.080 | 1.280 | |
| 2402 | 86 | 4.6 | 215 | 16.7 | 1.28 | 0.855 (0.652-1.122) | 0.258 | 4.128 | |
| 0203 | 46 | 7.8 | 140 | 10.9 | 4.195 | 0.696 (0.491-0.986) | 0.041 | 0.656 | |
| 3303 | 49 | 8.3 | 138 | 10.7 | 2.55 | 0.758 (0.538-1.066) | 0.110 | 1.760 | |
| 0207 | 76 | 12.9 | 114 | 8.9 | 7.362 | 1.529 (1.123-2.081) | 0.007 | 0.112 | |
| 0201 | 41 | 70 | 87 | 6.7 | 0.03 | 1.035 (0.704-1.520) | 0.862 | 13.792 | |
| 0206 | 23 | 3.9 | 48 | 3.7 | 0.038 | 1.052 (0.633-1.746) | 0.846 | 13.536 | |
| 3101 | 5 | 0.9 | 31 | 2.4 | 5.196 | 0.348 (0.135-0.899) | 0.023 | 0.368 | |
| 0301 | 5 | 0.9 | 24 | 1.9 | 2.722 | 0.452 (0.171-1.190) | 0.099 | 1.584 | |
| 2601 | 11 | 1.9 | 22 | 1.7 | 0.062 | 1.097 (0.528-2.277) | 0.804 | 12.864 | |
| 1102 | 16 | 2.7 | 19 | 1.5 | 3.423 | 1.868 (0.954-3.659) | 0.064 | 1.024 | |
| 3001 | 15 | 2.6 | 19 | 1.5 | 2.626 | 1.748 (0.882-3.465) | 0.105 | 1.680 | |
| 2901 | 3 | 0.5 | 17 | 1.3 | 2.49 | 0.385 (0.112-1.318) | 0.115 | 1.840 | |
| 2407 | 4 | 0.7 | 16 | 1.2 | 1.209 | 0.545 (0.181-1.636) | 0.272 | 4.352 | |
| 0101 | 14 | 2.4 | 8 | 0.6 | 10.788 | 3.902 (1.628-9.354) | 0.001 | 0.016 | |
| others | 3 | 0.5 | 23 | 1.8 | 4.806 | 0.282 (0.084-0.943) | 0.028 | 0.448 | |