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. 2018 Jan 20;38(1):34–41. [Article in Chinese] doi: 10.3969/j.issn.1673-4254.2018.01.06

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C1236T和C3435T不同基因型患者细胞遗传学复发的风险

Risk of cytogenetic relapse in patients with different genotypes of C1236T and C3435T

SNPs	Genotype	Study group (n=50)	Control group (n=50)	χ²	P	OR (95% CI)
MDR1-C1236T (rs1128503)
	CC	11(78.57%)	3(21.43%)	5.316	0.021	4.419 (1.151, 16.967)
	CT+TT	39 (45.35%)	47 (54.65%)	5.316	0.021	4.419 (1.151, 16.967)
	TT	7 (33.33%)	14(66.67%)	2.954	0.086	0.419 (0.153, 1.149)
	CC+CT	43 (54.44%)	36 (45.56%)	2.954	0.086	0.419 (0.153, 1.149)
MDR1-C3435T (rs1045642)
	CC	11(73.33%)	4(26.67%)	3.843	0.049	3.244 (0.956, 11.001)
	CT+TT	39 (45.88%)	46 (54.12%)	3.843	0.049	3.244 (0.956, 11.001)
	TT	12(31.58%)	26 (68.42%)	8.319	0.004	0.291 (0.124, 0.684)
	CC+CT	38 (61.29%)	24 (38.71%)	8.319	0.004	0.291 (0.124, 0.684)