6.

伊马替尼引起的血液毒性时间的发生情况比较

Comparison of the incidence of blood toxicity caused by imatinib between the two groups

Parameter	Study group (n=50)	Control group (n=50)	χ2	P
Hematological toxicity	31 (60.78%)	20 (39.22%)	4.842	0.028
Hematological toxicity requiring dose interruption/ dose reduction	25 (59.52%)	17 (40.47%)	2.627	0.105
Pancytopenia	1 (50.00%)	1 (50.00%)	0	1.000
Thrombocytopenia	25 (54.35%)	21 (45.65%)	0.644	0.422
Thrombocytopenia requiring dose interruption	20 (57.14%)	15 (42.86%)	1.099	0.295
Thrombocytopenia requiring dose reduction	15 (68.18%)	7(31.82%)	3.730	0.054
Neutropenia	17 (70.83%)	7(29.17%)	5.482	0.019
Neutropenia requiring dose interruption	9 (56.25%)	7 (43.75%)	0.298	0.585
Neutropenia requiring dose reduction	8 (66.67%)	4 (33.33%)	1.515	0.218
Anemia	2 (66.67%)	1 (33.33%)	0.344	0.558