3.

感染EV71后各组小鼠大脑皮质神经元的损伤情况图
Vimentin-mediated damages of the brain in mice infected with EV71 evaluated by immunohistochemical staining (Original magnification: ×400). A: WT mice infected with 1×108 TCID50 of EV71; B: VIM-/- mice infected with 1×108 TCID50 of EV71; C: Control mice treated with PBS; D: Neuron counts in the brain tissues by Image J software, showing greater relative number of neurons in VIM-/- mice than in WT mice (*P < 0.05 vs VIM-/- EV71 infection group).