2.

Claudin-3在癌组的表达及强阳性表达率与临床病理参数之间的关系

Expression of claudin-3 in the cancer tissues and the relationship between its strongly positive expression rate and the clinicopathological parameters of the patients

Clinicopathological parameter	n	Negative（-）	Positive（+）	Strongly positive（++）	Positive expression rate	Strongly positive expression rate	χ2	P
The P value and χ2 value were the result of comparison with the strongly positive expression rate in each subgroup.
Gender
Male	25	3	14	8	88%	32%	1.778	0.182
Female	15	0	7	8	100%	53.33%
Age (year)
≥60	20	2	13	5	90%	25%	3.75	0.105
< 60	20	1	8	11	95%	55%
Location of tumour
Colon	30	3	17	10	90%	33.33%	2.222	0.136
Rectum	10	0	4	6	100%	60%
Tumor size (cm)
< 5	20	2	11	7	90%	35%	0.417	0.519
≥5	20	1	10	9	95%	45%
N classification
N1-2	18	1	6	11	94.44%	61.11%	6.077	0.014
N0	22	2	15	5	90.91%	22.72%
Degree of differentiation
Well	14	2	9	3	85.71%	21.43%	8.186	0.017
Moderate	19	1	11	7	94.73%	36.84%
Poor	7	0	1	6	100%	85.71%