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. 2019 Sep 17;16(18):3457. doi: 10.3390/ijerph16183457

Table 4.

Comparisons of blood-based biomarkers between the frail and the non-frail phenotype.

Biomarkers Frail (n = 58) Non-Frail (n = 60) p-Value
Inflammatory Biomarkers
* C-reactive protein, mg/L 0.67 ± 0.13 0.40 ± 0.05 0.033
* Interleukin-6, pg/mL 20.01 ± 8.14 5.80 ± 0.55 0.044
Endocrine biomarkers
Insulin-like growth factor-1, ng/mL 29.96 ± 0.85 28.47 ± 0.80 0.103
Immunosenescence biomarkers
% CD4+ T cell 36.62 ± 1.07 33.88 ± 1.07 0.073
% CD8+ T cell 20.02 ± 0.96 19.67 ± 0.92 0.794
CD4:CD8 Ratio 2.13 ± 0.13 2.06 ± 1.19 0.735

* 0.01< p < 0.05, ** p < 0.01 (Data are represented as mean ± SE and Statistical significance using the independent t-test).