Table 1.
Participants’ baseline characteristics.
| Total n = 129 |
Varenicline n = 101 (78.3%) |
NRT n = 28 (21.7%) |
||
|---|---|---|---|---|
| Variable | Mean ± SD or N (%) | Mean ± SD or N (%) | p-Value * | |
| Demographics | ||||
| Age (years) | 65.9 ± 5.7 | 66.0 ± 5.9 | 65.4 ± 5.1 | 0.58 |
| Men | 109 (84.5) | 83 (82.2) | 26 (92.9) | 0.17 |
| Weight (kg) | 68.5 ± 11.1 | 68.4 ± 11.7 | 68.9 ± 9.1 | 0.83 |
| Smoking year (years) | 40.9 ± 11.1 | 40.6 ± 11.1 | 41.9 ± 11.3 | 0.59 |
| Cigarettes/days | 21.8 ± 11.1 | 22.0 ± 10.5 | 20.8 ± 13.3 | 0.59 |
| Pack-years | 43.7 ± 23.5 | 44.4 ± 23.6 | 41.3 ± 23.5 | 0.53 |
| Pack-years ≥ 30 | 94 (72.9) | 73 (72.3) | 21 (75.0) | 0.77 |
| Exhaled CO (ppm) | 14.2 ± 8.5 | 14.6 ± 8.6 | 13.0 ± 8.2 | 0.39 |
| CO ≥ 18 ppm | 35 (27.1) | 29 (28.7) | 6 (21.4) | 0.44 |
| FTND score | 6.2 ± 2.6 | 6.0 ± 2.5 | 6.8 ± 2.6 | 0.12 |
| FTND Score ≥ 7 | 59 (45.7) | 42 (41.6) | 17 (60.7) | 0.07 |
| Treatment method | ||||
| Pharmacotherapy | 56 (43.4) | 40 (39.6) | 16 (57.1) | 0.10 |
| Pharmacotherapy with individual counseling | 73 (56.6) | 61 (60.0) | 12 (42.9) | |
| Comorbidities | ||||
| Hypertension | 65 (50.4) | 51 (50.5) | 14 (50.0) | 0.96 |
| Diabetes | 30 (23.3) | 25 (24.8) | 5 (17.9) | 0.44 |
| Hyperlipidemia | 50 (45.0) | 46 (45.5) | 12 (42.9) | 0.80 |
| Heart disease | 31 (24.0) | 27 (26.7) | 4 (14.3) | 0.17 |
| Lung disease | 15 (11.6) | 9 (8.9) | 6 (21.4) | 0.07 |
| Neurological disease | 17 (13.2) | 13 (12.9) | 4 (14.2) | 0.84 |
| Cancer | 6 (4.7) | 4 (4.0) | 2 (7.1) | 0.48 |
| Psychiatric disease | 16 (12.4) | 11 (10.9) | 5 (17.9) | 0.32 |
Abbreviations: CO = carbon monoxide; FTND score = Fagerström test for nicotine dependence score; NRT = nicotine replacement therapy; SD = standard deviation; * using chi-squared and t-test.