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. Author manuscript; available in PMC: 2019 Sep 29.
Published in final edited form as: Bioconjug Chem. 2019 Jan 29;30(2):366–383. doi: 10.1021/acs.bioconjchem.8b00761

Figure 8.

Figure 8.

Molecular structure of GRN163L. The lipid oligonucleotide GRN163L, 5′-Palm-TAGGGTTAGACAA-NH2-3′, with a thiophosphoramidate internucleosidic linkage (top) and its structural formula (down).