Table 2.
The cutoff value of CD16+CD56+ NK cells in prediction of different CRC stages.
| Groups | AUC | Threshold (% in lymphocytes) | Case numbers∗ | OR (95% CI) | p value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|---|---|---|
| Healthy vs. cancer | 0.725 | 19.7 | 48/60: 61/264 | 0.08 (0.04, 0.15) | <0.001 | 80.0 | 76.9 | 44.0 | 94.4 |
| Healthy+stages 1&2 vs. stages 3&4 | 0.892 | 15.6 | 157/186: 38/138 | 0.07 (0.04, 0.12) | <0.001 | 84.4 | 72.5 | 80.5 | 77.5 |
| Stages 1&2 vs. stages 3&4 | 0.878 | 15.6 | 109/126: 38/138 | 0.06 (0.03, 0.11) | <0.001 | 86.5 | 72.5 | 74.2 | 85.5 |
AUC: area under the curve. ∗Case number above the threshold/total case number in corresponding groups.