Table 4.
The effect of high-salt intake on the frequencies of cells expressing CD11b/c, CD11a, and CD49d on peripheral blood leukocyte subpopulations of Sprague-Dawley rats.
| Peripheral blood leukocytes | LS diet | HS diet | p |
|---|---|---|---|
| Granulocytes % parent | 8.86 ± 2.82 | 14.5 ± 6.98 | 0.004 ∗ |
| CD11b/c+ granulocytes % parent | 100.0 ± 0.01 | 100.0 ± 0.01 | 1.000 |
| CD11a+ granulocytes % parent | 97.7 ± 2.64 | 97.6 ± 2.14 | 0.858 |
| CD49d granulocytes % parent | 90.1 ± 6.74 | 86.3 ± 6.66 | 0.111 |
| Monocytes % parent | 17.5 ± 4.77 | 18.4 ± 3.60 | 0.553 |
| Non-CD3 mononuclear cells % parent | 78.6 ± 9.95 | 85.4 ± 8.49 | 0.039 ∗ |
| CD11b/c+ monocytes % parent | 85.5 ± 5.38 | 83.2 ± 11.1 | 0.438 |
| CD11a total monocytes % parent | 99.5 ± 0.35 | 99.1 ± 0.80 | 0.209 |
| CD11ahigh monocytes % parent | 53.7 ± 7.45 | 45.7 ± 10.4 | 0.015 ∗ |
| CD49d total monocytes % parent | 97.3 ± 1.41 | 94.7 ± 4.46 | 0.025 ∗ |
| CD49dhigh monocytes % parent | 57.5 ± 11.1 | 42.3 ± 13.5 | 0.001 ∗ |
| CD49ddim monocytes % parent | 39.7 ± 11.8 | 52.1 ± 11.5 | 0.004 ∗ |
| Lymphocytes % parent | 63.6 ± 5.49 | 55.2 ± 8.89 | 0.002 ∗ |
| CD3+ lymphocytes % parent | 46.9 ± 5.11 | 45.6 ± 4.52 | 0.434 |
| CD11b/c+CD3+ lymphocytes % parent | 0.31 ± 0.25 | 0.50 ± 0.33 | 0.077 |
| CD11b/c+ B cells % parent | 4.89 ± 2.37 | 6.65 ± 3.18 | 0.064 |
| CD11a+CD3+ T cells % parent | 99.9 ± 0.02 | 99.9 ± 0.02 | 0.132 |
| CD11a+ cytotoxic lymphocytes % parent | 100.00 | 100.00 | 1.000 |
| CD11a+ helper % parent | 100.00 | 100.00 | 1.000 |
| CD49d+CD3+ lymphocytes % parent | 98.4 ± 1.12 | 96.2 ± 3.89 | 0.034 ∗ |
| CD49d+CD3+ high lymphocytes % parent | 5.45 ± 2.38 | 7.42 ± 1.82 | 0.011 ∗ |
| CD49d+ cytotoxic lymphocytes % parent | 99.9 ± 0.07 | 99.8 ± 0.15 | 0.071 |
| CD49d+ T helper % parent | 98.6 ± 0.72 | 98.1 ± 1.16 | 0.137 |
| CD49d+ B cells % parent | 99.9 ± 0.04 | 94.9 ± 7.43 | 0.008 ∗ |
LS: low-salt diet; HS: high-salt diet; n = 24 per group; data was compared using t-test, and p < 0.05 was considered significant.