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. 2019 Sep 15;2019:4616034. doi: 10.1155/2019/4616034

Figure 6.

Figure 6

Western blotting analysis showing that DR-Ab stimulated AMPK/Sirt-3/PPARγ signaling pathway. (a) Time-course study showing the effect of DR-Ab on AMPK phosphorylation. (b–d) DR-Ab reversed the effect of Ang II on p-AMPK (b), PPARγ (c), & Sirt-3 (d). n = 4‐6. (e) 3-TYP eliminated DR-Ab effect on the PPARγ level in Ang II-treated cells. n = 4. (f, g) Compound C abolished the effect of DR-Ab on the protein expression of PPARγ (f) and Sirt-3 (g) in Ang II-treated cells. n = 4‐6. ∗p < 0.05 versus control group, †p < 0.05 versus Ang II alone group, ‡p < 0.05 versus Ang II+ DR-Ab.