Table 2.
MiRNA levels in the PTC, benign nodule, and the healthy control groups in the validation set by qRT-PCRa.
miRNA | PTC (n = 64) | Benign nodule (n = 55) | Healthy control (n = 57) | P valueb | P valuec | P valued |
---|---|---|---|---|---|---|
miR-222-3p | 0.415 ± 0.030 | 0.390 ± 0.026 | 0.290 ± 0.020 | 0.536 | <0.001 | <0.01 |
miR-17-5p | 1.590 ± 0.139 | 1.771 ± 0.159 | 1.152 ± 0.086 | 0.391 | <0.05 | <0.001 |
miR-451a | 0.964 ± 0.060 | 0.862 ± 0.045 | 0.639 ± 0.030 | 0.188 | <0.001 | <0.001 |
miR-146a-5p | 1.627 ± 0.082 | 1.816 ± 0.094 | 2.065 ± 0.113 | 0.128 | <0.01 | 0.092 |
miR-132-3p | 1.442 ± 0.067 | 1.566 ± 0.086 | 2.052 ± 0.104 | 0.247 | <0.001 | <0.001 |
miR-183-3p | 0.527 ± 0.042 | 0.500 ± 0.033 | 0.733 ± 0.035 | 0.619 | <0.001 | <0.001 |
PTC: papillary thyroid cancer. aThe relative contents of miRNAs are normalized to let-7d/g/i and presented as the mean ± SEM. bDifference between the PTC group and the benign nodule group. cDifference between the PTC group and the healthy control group. dDifference between the benign nodule group and the healthy control group.