Table 3.

Differentially expressed miRNAs among the MTC, benign nodule, and the healthy control groups by qRT-PCR^a.

miRNA	MTC (n = 15)	Benign nodule (n = 15)	Healthy control (n = 15)	P valueb	P valuec	P valued
miR-222-3p	0.731 ± 0.035	0.376 ± 0.066	0.253 ± 0.028	<0.001	<0.001	0.098
miR-17-5p	2.719 ± 0.184	1.669 ± 0.322	1.079 ± 0.163	<0.01	<0.001	0.113
miR-451a	0.803 ± 0.028	0.836 ± 0.043	0.629 ± 0.059	0.533	<0.05	<0.01

MTC: medullary thyroid carcinoma. ^aThe relative contents of miRNAs are normalized to let-7d/g/i and presented as mean ± SEM. ^bDifference between the MTC group and the benign nodule group. ^cDifference between the MTC group and the healthy control group. ^dDifference between the benign nodule group and the healthy control group.