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. 2019 Sep 15;2019:5613417. doi: 10.1155/2019/5613417

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Copyright © 2019 Yang Li et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Relative expression of miR-199a-5p in leukemia cell lines and AML samples. miR-199a-5p was measured by qRT-PCR in 32 relapsed/refractory AML bone marrow samples and 11 complete remission AML bone marrow samples (a) and K562 and K562/ADM cells (b) using U6 for normalization. (c) The inhibitory effect of ADM on K562 and K562/ADM cells was detected by the MTT assay. After treatment with various concentrations of ADM, growth inhibition was assessed. IC₅₀ of K562/ADM (146.14 ± 0.079 μg/ml) was 48.7-fold than that of K562 (3.08 ± 0.056 μg/ml).