TABLE 5.

Associations between the prudent dietary pattern and presence/abundance of specific taxa at the level of genera/operational taxonomic unit¹

			Relative abundance among participants with taxon present, %
Taxon	Reference no.	Prevalence, %	Median	IQR		β coefficient2	False discovery rate–adjusted P value3
g. CC-1154	807548	36.4	0.013	0.005	0.042	−0.53	<0.001
g. Ruminococcus4	583398	97.9	0.099	0.029	0.283	−0.46	<0.001
g. Desulfovibrio4	4453773	72.5	0.093	0.006	0.322	−0.39	0.025
g. Coprobacillus4	587933	60.7	0.009	0.004	0.020	−0.32	0.002
f. Rikenellaceae	357046	100.0	1.55	0.75	3.10	−0.31	0.025
g. Cloacibacillus	3121406	22.6	0.010	0.004	0.040	−0.27	0.038
g. Collinsella4	147071	79.9	0.050	0.022	0.096	−0.26	0.024
g. Dorea4	523542	99.6	0.146	0.078	0.270	−0.19	0.038
g. Cetobacterium	828162	13.7	0.002	0.002	0.003	0.20	0.024
g. Clostridium	558420	99.4	0.216	0.068	0.656	0.28	0.038
o. Streptophyta4	262379	42.6	0.006	0.003	0.015	0.30	0.004
g. Lachnospira4	843553	99.6	0.828	0.302	1.603	0.30	0.025
f. Victivallaceae	158404	30.0	0.034	0.009	0.109	0.31	0.038
g. Veillonella	342427	79.5	0.020	0.006	0.074	0.32	0.025
g. Faecalibacterium4	368219	100.0	7.0	3.0	11.7	0.36	0.024
g. Paraprevotella4	165118	81.8	0.006	0.003	0.656	0.57	0.024

¹ n = 517. f., family; g., genus; o., order.

²β Coefficient is log2 fold change, estimated with metagenomeSeq. The multivariable model included age, race, clinical center, energy intake, BMI, and library size.

³Derived from a modified t test.

⁴Associated with the Western dietary pattern, in the opposite direction.