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. 2019 Sep 24;13:3391–3404. doi: 10.2147/DDDT.S222296

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© 2019 Wang et al.

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Protection of paclitaxel on organ injuries in septic mice. (A–D) Representative morphological images at 6 and 24 hrs by HE staining were presented to assess the injury severity of lungs, heart, kidney and liver. (E, G, I, K) Histological scores of organ injury were calculated. Lung wet/dry ratio (F), sera creatine kinase (H), sera creatinine (J) and sera alanine aminotransferase (L) were also tested. Samples were harvested at 6 and 24 hrs after CLP. Data represent means ± SD (n=6). *P<0.05, **P<0.01, ***P<0.001.