Table 4.

Fasting blood parameters from experimental protocol 3

Fasting Blood Parameter	Lean	Obese	Obese + Bosentan
Cholesterol, mg/dL	71.3 ± 1.8	870.4 ± 38.7*	817.4 ± 66.0*
Triglycerides, mg/dL	181.6 ± 20.2	584.5 ± 60.6*	664.0 ± 97.1*
HDL, mg/dL	45.6 ± 1.2	88.5 ± 5.0*	90.3 ± 5.7*
LDL, mg/dL	3.1 ± 0.1	270.9 ± 14.2*	254.3 ± 22.7*
NEFA, mmol/L	0.73 ± 0.05	0.78 ± 0.04	0.82 ± 0.06
Insulin, ng/dL	0.6 ± 0.1	3.1 ± 0.4*	2.5 ± 0.5*
Glucose, mg/dL	241.1 ± 11.0	332.0 ± 13.1*	307.3 ± 11.5*

Values are means ± SE. NEFA, nonesterified fatty acid.

^*P < 0.05 vs. lean.