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. 2019 Jul 12;33(10):10872–10888. doi: 10.1096/fj.201900767R

Figure 1.

Figure 1

Sirt6 blocks Pal-mediated insulin resistance of cardiomyocytes. A) H9c2 cardiomyocytes were overexpressed with Ad.Sirt6 or an empty vector. Cells were grown in DMEM with or without insulin and treated with Pal for 24 h. Glucose uptake was measured by estimating transport of fluorescent analog 2-NBDG by FACS analysis. Values are means ± se; n = 6. B) Western blot analysis showing expression levels of different proteins 24 h after Pal treatment of cells. Results are shown for duplicate samples. C–E) Densitometric quantitation of the Western blots; means ± se; n = 3.