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DRP1 overexpression had no further effect on Dox-induced cell death. H9c2 cells were infected with AdDRP1or adenovirus expressing β-galactosidase (Adβ-gal) for 24 h and then exposed to either Dox (750 nM) or saline for 24 h. Cell death was determined by PI staining (A) and cleavage of caspase-3 and PARP (B). Scale bars, 200 μm. Data are expressed as means ± se and were analyzed by 1-way ANOVA. *P < 0.05 vs. β-gal (n = 3).
