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. 2019 Jul 11;127(3):770–780. doi: 10.1152/japplphysiol.00366.2019

Fig. 5.

Fig. 5.

Sleep lost during sleep deprivation (SD) vs. sleep rebound during the first 16 h after SD. Black bars show sleep lost during the respective SD periods; losses were calculated from baseline values for duration of (A and B) non-rapid eye movement sleep (NREMS) and (C and D) rapid eye movement sleep (REMS) (see Fig. 1). More sleep was lost during the SD occurring during zeitgeber time (ZT)20–ZT4 (A and C) because mice sleep more during that period than during ZT8–ZT16. After SD during ZT20–ZT4, only wild-type (WT) mice had a NREMS rebound occurring between ZT4–ZT20 (A); values occurring after SD were compared with control values from the same mice (differences between those values are shown in the black bars). No NREMS rebound occurred after SD between ZT8–ZT16 (B). All strains showed a REMS rebound after both SD conditions (C and D). Values shown are means ± SE. #P < 0.05 ZT4 vs. ZT16; *P < 0.05 baseline vs. post-SD recovery. AcP, interleukin-1 receptor accessory protein; AcPb, brain-specific AcP.