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. 2019 Jul 11;127(3):770–780. doi: 10.1152/japplphysiol.00366.2019

Fig. 8.

Fig. 8.

Graphic representation ± SE of quantified phosphorylated (p)-p38MAPK with respect to total p38MAPK in non-sleep deprived (non-SD) animals (A) and SD animals (B). Wild-type animals at zeitgeber time (ZT)16 had significantly more p-p38MAPK than their ZT4 counterparts (Tukey adjusted P value < 0.05). This was also reflected in brain-specific interleukin-1 receptor accessory protein (AcPb) knockout (KO) animals (Tukey adjusted P value < 0.005) but not in AcP KO animals. However, at ZT4, AcP KO animals had significantly more p-p38MAPK when compared with AcPb KO animals (Tukey adjusted P value < 0.005). These significant differences were mirrored after sleep deprivation (C). **P < 0.005, *P < 0.05.