Skip to main content
. Author manuscript; available in PMC: 2019 Sep 30.
Published in final edited form as: Sci Immunol. 2019 May 3;4(35):eaax0416. doi: 10.1126/sciimmunol.aax0416

Fig. 1.

Fig. 1.

IL-33 regulates ILC2 activity and eosinophil numbers. (A) Body weight of wild type (WT) and Il33−/− mice on conventional diet at 16 weeks of age. (n = 4) (B) Mass of indicated adipose depots in WT and Il33−/− mice at 16 weeks of age. (n = 4) (C) Proportion of combined white adipose tissue (WAT) mass of epididymal (ewat), mesenteric (mwat) and inguinal (iwat) depots as percent of body weight in WT and Il33−/− mice at 16 weeks of age. (n = 4) (D) ILC2 numbers and proportions in visceral adipose compartments of WT and Il33−/− mice. (n ≥ 3) Data pooled from two individual experiments. (E and F) Representative dot plots (E) and quantification (F) showing intracellular IL-5 and IL-13 staining in ILC2s from visceral adipose depots of WT and Il33−/− mice. (n = 3) (G and H) Representative dot plots (G) and quantification (H) of macrophages and eosinophils in visceral adipose depots of WT and Il33−/− mice. (n = 3). Mean ± SEM, * P < 0.05, ** P < 0.01, ***P < 0.001, ns - not significant, Student’s t-test.