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. 2019 Feb 1;125(8):1301–1312. doi: 10.1002/cncr.31909

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© 2019 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Participant flow. In both the PreChemo (first vaccination 8‐30 days before the start of a chemotherapy cycle) and OnChemo (first vaccination at the start of a chemotherapy cycle) strata, the second vaccination took place 1‐2 months after the first vaccination and at the first day (allowing a window of ±1 day) of a subsequent cycle of chemotherapy. Some participants who were randomized to the PreChemo stratum and were required to wait 8‐30 days after vaccination before they could start chemotherapy chose to withdraw so as to proceed to chemotherapy immediately. ATP, according‐to‐protocol; CMI, cell‐mediated immunogenicity; M, month; n, number of patients attending a visit; pIMD, potential immune‐mediated disease; RZV, recombinant zoster vaccine; SAE, serious adverse event; TVC, total vaccinated cohort.