Table 3.
Univariate and multivariate binary regression analysis to determine independent risk factors for presence of erectile dysfunction
| Univariate OR (95% CI) | Univariate P‐value | MV Model 1, First‐Step OR (95% CI); P‐value | MV Model 1, Last‐Step OR (95% CI); P‐value | MV Model 2, First‐Step OR (95% CI); P‐value | MV Model 2, Last‐Step OR (95% CI); P‐value | |
|---|---|---|---|---|---|---|
| CPS | B:1.48 (0.55‐3.99) | .438 | ||||
| C: 5.687 (1.09‐29.7) | .039 | |||||
| MELD | 1.15 (1.02‐1.28) | .019 | 1.2 (0.99‐1.46); P = .059 | 1.19 (1.03‐1.36); P = .015 | ||
| HVPGa | 1.11 (1.007‐1.232) | .036 | 1.10 (0.99‐1.22); P = .068 | 1.11 (1.002‐1.23); P = .045 | ||
| Previous hepatic decompensation | 2.71 (1.04‐7.07) | .042 | 2.5 (0.59‐10.9); P = .207 | |||
| Presence of esophageal varicesb | 1.41 (0.54‐3.7) | .483 | ||||
| Creatinine | 22.29 (1.4‐354.6) | .028 | ||||
| Albumin | 0.915 (0.84‐0.99) | .038 | 1.07 (0.89‐1.28); P = .48 | |||
| Age | 1.078 (1.018‐1.141) | .010 | 1.07 (0.98‐1.18); P = .129 | 1.08 (0.99‐1.18); P = .086 | ||
| BMI | 1.106 (0.982‐1.246) | .096 | ||||
| Art. HTN | 4.74 (1.44‐15.62) | .011 | 4.86 (0.83‐26.6); P = .080 | 6.36 (1.16‐34.85); P = .033 | 2.94 (0.64‐13.58); P = .167 | |
| DM | 4.37 (1.33‐14.44) | .015 | 7.98 (1.22‐52.31); P = .030 | 7.4 (1.31‐41.75); P = .023 | 3.42 (0.59‐19.87); P = .172 | 4.29 (0.79‐23.37); P = .092 |
| BBc | 1.97 (0.76‐5.07) | .163 | ||||
| HCC | 2.15 (0.42‐11.1) | .362 | ||||
| Anti‐Depressive Medication | 1.47 (0.27‐8.09) | .660 | ||||
| Depression | 1.34 (0.37‐4.81) | .654 | ||||
| Active Smoker | 0.41 (0.16‐1.035) | .059 | ||||
| Impaired Libido | 6.61 (2.36‐18.55) | <.001 | 2.44 (0.57‐10.51); P = .23 | |||
| BT | 0.401 (0.18‐0.91) | .028 | 1.09 (0.28‐4.25); P = .90 | |||
| TT | 0.837(0.71‐0.98) | .029 | ||||
| PRL | 1.01 (0.959‐1.06) | .715 | ||||
| LH | 1.06 (0.93‐1.21) | .379 | ||||
| FSH | 1.009 (0.945‐1.077) | .785 | ||||
| SHBG | 0.991 (0.979‐1.004) | .163 |
MV Model 1 First‐step: Odds‐ratio for all variables included in the multivariate binary regression model (stepwise‐backwards; variables: MELD, Albumin, Age, art. HTN, DM, Libido, previous hepatic decompensation and BT).
MV Model 1 Last‐step: Odds‐ratio for variables still significantly associated with presence of ED in the last‐step of the multivariate binary regression model (stepwise‐backwards).
MV Model 2 First‐step: Odds‐ratio for all variables included in the multivariate binary regression model in the subgroup of patients with available HVPG (stepwise‐backwards; variables: art. HTN, DM, HVPG).
MV Model 2 Last‐step: Odds‐ratio for variables still significantly associated with present of ED in the last‐step of the multivariate binary regression model in the subgroup of patients with available HVPG.
HVPG was available in 48 patients.
Status on esophageal varices was available in 74 patients.
BB status was available in 75 patients, in 5 patients no information on BB intake was available due to uncertain duration and frequency of BB intake.