Figure 6.

Effects of platycodigenin (PLA) on Aβ25-35-induced neuronal death. Primary cultured cortical neurons were cultured for 3 d and treated with PLA (1 and 10 μM) and/or Aβ25-35 (10 μM) for another 3 d. The neuronal viability was determined by CCK8 analysis. The data are normalized to the control and shown as the mean ± SEM of three independent experiments. Each group has five replicates in the independent experiment. **p < 0.01 and ***p < 0.001 versus vehicle (Veh), Kruskal-Wallis one-way analysis of variance by ranks test.