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. 2019 Sep 10;24(18):3287. doi: 10.3390/molecules24183287
α-CHCA Alpha-Cyano-4-Hydroxycinnamic Acid
ADC Antibody-Drug Conjugate
ARC Antibody-siRNA Conjugate
ASGPR Asialoglycoprotein Receptor
ASO Antisense Oligonucleotide
DAR Drug-Antibody Ratio
DBCO Dibenzylcyclooctyne
DCM Dichloromethane
DIA Diisopropylamine
DIPEA N,N-Diisopropylethylamine
DMF Dimethyl Formamide
EDTA Ethylenediaminetetraacetic Acid
FACS Fluorescence Activated Cell Sorting
FITC Fluorescein Isothiocyanate
FPLC Fast Protein Liquid Chromatography
GalNAc N-Acetylgalactosamine
GMP Good Manufacturing Practice
HC Antibody Heavy Chain
kDa Kilodalton
KF KAYA-PEG6-K-Fluorescein
KN3 K-PEG6-SG-K-N3
LC Antibody Light Chain
LNP Lipid Nanoparticle
mAb Monoclonal Antibody
MALDI-TOF Matrix Assisted Laser Desorption Ionization Time-of-Flight
MTGase Microbial Transglutaminase
MWCO Molecular Weight Cutoff
NATs Nucleic Acid Therapeutics
PBS Phosphate Buffered Saline
PCR Polymerase Chain Reaction
PD Pharmacodynamic
PK Pharmacokinetic
PS Phosphorothioate
RP-HPLC Reverse Phase High Performance Liquid Chromatography
SDS-PAGE Sodium Dodecylsulfate Polyacrylamide Gel Electrophoresis
SEC Size Exclusion Chromatography
siRNA Small Interfering Ribonucleic Acid
SPAAC Strain-Promoted Azide-Alkyne Cycloaddition
TEG Triethylene Glycol