α-CHCA |
Alpha-Cyano-4-Hydroxycinnamic Acid |
ADC |
Antibody-Drug Conjugate |
ARC |
Antibody-siRNA Conjugate |
ASGPR |
Asialoglycoprotein Receptor |
ASO |
Antisense Oligonucleotide |
DAR |
Drug-Antibody Ratio |
DBCO |
Dibenzylcyclooctyne |
DCM |
Dichloromethane |
DIA |
Diisopropylamine |
DIPEA |
N,N-Diisopropylethylamine |
DMF |
Dimethyl Formamide |
EDTA |
Ethylenediaminetetraacetic Acid |
FACS |
Fluorescence Activated Cell Sorting |
FITC |
Fluorescein Isothiocyanate |
FPLC |
Fast Protein Liquid Chromatography |
GalNAc |
N-Acetylgalactosamine |
GMP |
Good Manufacturing Practice |
HC |
Antibody Heavy Chain |
kDa |
Kilodalton |
KF |
KAYA-PEG6-K-Fluorescein |
KN3 |
K-PEG6-SG-K-N3 |
LC |
Antibody Light Chain |
LNP |
Lipid Nanoparticle |
mAb |
Monoclonal Antibody |
MALDI-TOF |
Matrix Assisted Laser Desorption Ionization Time-of-Flight |
MTGase |
Microbial Transglutaminase |
MWCO |
Molecular Weight Cutoff |
NATs |
Nucleic Acid Therapeutics |
PBS |
Phosphate Buffered Saline |
PCR |
Polymerase Chain Reaction |
PD |
Pharmacodynamic |
PK |
Pharmacokinetic |
PS |
Phosphorothioate |
RP-HPLC |
Reverse Phase High Performance Liquid Chromatography |
SDS-PAGE |
Sodium Dodecylsulfate Polyacrylamide Gel Electrophoresis |
SEC |
Size Exclusion Chromatography |
siRNA |
Small Interfering Ribonucleic Acid |
SPAAC |
Strain-Promoted Azide-Alkyne Cycloaddition |
TEG |
Triethylene Glycol |