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. 2019 Sep 12;24(18):3319. doi: 10.3390/molecules24183319

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of fucoidan from Fucus vesiculosus (FvF) on on glucose transport. FvF on the 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) transport in Caco-2 monolayer model (a) and glucose transport in everted gut sac model (b). Caco-2 monolayer model and everted gut sac model were treated with 0, 20, 50, or 100 μg/mL of FvF. Oral glucose tolerance test (OGTT) was conducted with eight-week-old male kunming mice (c). Mice were perfused with 20 or 100 mg/kg of FvF 30 min before oral glucose administion (2 g/kg body weight). Data are expressed as the mean ± SEM. Differences were assessed by ANOVAs and statistical results are denoted as follows: * p < 0.05 versus the control group.