Figure 2.

Mean (± SD) time courses of plasma emicizumab concentration following a single subcutaneous injection of 1 mg/kg with the old drug product into the abdomen (group A), a single subcutaneous injection of 1 mg/kg with the new drug product into the abdomen (group B), upper arm (group C), and thigh (group D), and a single intravenous infusion of 0.25 mg/kg with the new drug product (group E). Data below the quantification range were handled as missing in summary statistics calculation. Summary statistics were not calculated when measured values were below the quantification range in the majority of subjects for each group and time point. a, Linear plot. b, Semilogarithmic plot.