Figure 1.

Tumor size in primary xenografts in BALB/c mice. Citral decreased tumor size in primary breast cancer xenografts. BALB/c mice bearing 4T1 cells as xenografts were treated with daily oral feeding of control or 50 mg/kg citral for 2 weeks. Panel A: Tumor volumes and panel B: Mice body weights were determined. Tumors in citral-treated mice were 50% of the size of control animals at the end of drug treatment. Data are presented as mean ± SD (n = 6), (mm³). (** P ˂ 0.01).