Table 1.
The cytotoxicity of compounds 3a–3k and fipronil on the Trichoplusia ni (Hi-5) cell and Spodoptera litura cell (SL) cell determined by the MTT Assay.
| Entry | Compounds | Inhibition (%) (X ± SE) Φ | |
|---|---|---|---|
| R | Hi-5 Cell | SL Cell | |
| 3a | -H | 72.85 ± 1.98 c | 40.83 ± 0.63 e |
| 3b | -Cl | 54.48 ± 2.91 e | 25.56 ± 0.61 h |
| 3c | -Br | 65.18 ± 1.97 d | 50.32 ± 0.57 d |
| 3d | -I | 86.90 ± 1.92 b | 20.14 ± 1.28 i |
| 3e | -Me | 44.36 ± 1.99 f | 6.57 ± 0.36 j |
| 3f | -Et | 96.80 ± 1.81 a | 5.22 ± 0.76 j |
| 3g | -Pr | 63.60 ± 2.00 d | 29.10 ± 0.46 g |
| 3h | -i-Pr | 36.56 ± 1.61 g | 33.81 ± 0.58 f |
| 3i | -n-Bu | 52.96 ± 2.94 e | 32.75 ± 0.60 f |
| 3j | -i-Bu | 39.86 ± 2.33 f,g | 67.89 ± 0.76 b |
| 3k | -t-Bu | 27.87 ± 2.61 h | 58.55 ± 0.71 c |
| fipronil | -SOCF3 | 97.54 ± 1.33 a | 75.93 ± 0.50 a |
Φ The level of significance was set at p < 0.05 and the values with the same letter indicated no significance.