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. 2019 Sep 13;24(18):3338. doi: 10.3390/molecules24183338

Table 1.

Chemical structures and International Union of Pure and Applied Chemistry (IUPAC) names of cannabinoid 2 receptor (CB2R) ligands used in EIU model.

Compound HU-308 HU-910 RO6871304 RO6871085 RO6851228
Chemical structure graphic file with name molecules-24-03338-i001.jpg graphic file with name molecules-24-03338-i002.jpg graphic file with name molecules-24-03338-i003.jpg graphic file with name molecules-24-03338-i004.jpg graphic file with name molecules-24-03338-i005.jpg
IUPAC name {(1S,4S,5S)-4-[2,6-Dimethoxy-4-(2-methyloctan-2-yl)phenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl}methanol {(1S,4R)-2-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-7,7-dimethylbicyclo[2.2.1]hept-2-en-1-yl}methanol (3S)-1-{5-tert-butyl-3-[(1-cyclopropyl-1H-tetrazol-5-yl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl}pyrrolidin-3-ol 5-Cyclopropyl-N-[(2S)-1-cyclopropyl-2-(5-methyl-1,2,4-oxadiazol-3-yl)propan-2-yl]-4-(2,2,2-trifluoroethoxy)pyridine-2-carboxamide 5-Cyclopropyl-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-4-[(3-methyloxetan-3-yl)methoxy]pyridine-2-carboxamide