Figure 4.

Impact of body weight on prebronchodilator forced expiratory volume in 1 second (FEV ₁) change from baseline for patients with baseline blood eosinophil counts ≥ 300 cells/μL receiving high‐dosage inhaled corticosteroids/long‐acting β₂‐agonists. Pbo, placebo; Q, quartile; Q8W, every 8 weeks. ^aSymbols represent the mean, and error bars are standard error of the mean. ^bQ1–Q3: 40–89 kg; Q4: > 89 kg. ^cBody weight cutoff = 115 kg (top 5%). [Colour figure can be viewed at wileyonlinelibrary.com]