Table 5.
Simulation study results[Link]
| (n 0,n 1) | i = 6 Studies | i = 12 Studies | |||||
|---|---|---|---|---|---|---|---|
| Pseudo IPD | REML HK | DL | Pseudo IPD | REML HK | DL | ||
| Coverage probability | (5, 5) | 96.2% | 95.6% | 89.4% | 95.4% | 95.2% | 90.4% |
| (10, 10) | 96.0% | 95.6% | 92.6% | 95.4% | 95.0% | 92.4% | |
| (40, 40) | 94.8% | 94.8% | 87.8% | 94.8% | 94.6% | 92.6% | |
| Bias | (5, 5) | 0.0583 | 0.0508 | 0.0159 | −0.0058 | −0.0061 | −0.0040 |
| (10, 10) | 0.0297 | 0.0300 | 0.0300 | −0.0014 | −0.0015 | −0.0010 | |
| (40, 40) | −0.0139 | −0.0139 | −0.0141 | −0.0103 | −0.0104 | −0.0117 | |
| Mean squared error (MSE) | (5, 5) | 0.8581 | 0.8603 | 0.9958 | 0.4653 | 0.4668 | 0.5621 |
| (10, 10) | 0.6052 | 0.6050 | 0.6514 | 0.3062 | 0.3068 | 0.3521 | |
| (40, 40) | 0.4050 | 0.4046 | 0.4034 | 0.2000 | 0.1998 | 0.1989 | |
Abbreviations: DL, DerSimonian‐Laird; n 0, number of subjects in control group; n 1, number of subjects in exposure group; REML HK, restricted maximum likelihood with Hartung‐Knapp correction. Coverage of the calculated 95% confidence intervals, mean bias, and MSE obtained with the different methods.