Table 1.
Patient Characteristics of the DINO Study Data Set (Study 1) and the Shared Data Set (Study 2)
| DINO Study Data (Study 1) | de Wildt et al19 (Study 2) | Combined Data Set | |
|---|---|---|---|
| Patients | 29 | 26 | 55 |
| Samples (samples per neonate) | 60 (2.1) | 172 (6.6) | 232 (4.9) |
| Doses (doses per neonate) | 123 (4.2) | 26 (1) | 149 (2.7) |
| Doses for stressful procedures (infusion duration ≤30 min) | 59 (2.0) | 26 (1) | 85 (1.5) |
| Doses for continuous sedation (infusion duration >30 min) | 65 (2.2) | 0 (0) | 65 (1.2) |
| Female neonates, N (%) | 13 (45%) | 16 (62%) | 29 (53%) |
| Gestational age, wka | 26.7 (24.0–31.1) | 28.1 (26.3–33.6) | 27.3 (24.0–33.6) |
| Birth weight, kg29 , a | 0.84 (0.47–1.8) | 1.1 (0.75–1.6) | 0.95 (0.47–1.8) |
| Postnatal age (at day of inclusion), da | 18 (1–88) | 5.5 (3–11) | 9 (1–88) |
| Actual body weight, kg29 , a | 1.3 (0.6–4.3) | 1.0 (0.77–1.6) | 1.1 (0.6–4.3) |
a
Data provided as medians and ranges.