Table 1.
Functional data after UUO and butaprost treatment
| Groups | Sham | Sham + butaprost | UUO | UUO + butaprost |
|---|---|---|---|---|
| Bodyweight (BW) (g) | 22.2 ± 0.6 | 22.8 ± 0.3 | 22.1 ± 0.5 | 22.1 ± 0.3 |
| Obstructed kidney/BW (mg/mg mice) | 5.8 ± 0.1 | 6.3 ± 0.3 | 7.5 ± 0.4* | 8.4 ± 0.1# |
| Creatinine (µmol/L) | 11.7 ± 0.8 | 10.6 ± 0.8 | 12.8 ± 1 | 11.3 ± 0.6 |
| BUN (mmol/L) | 7.5 ± 0.2 | 6.3 ± 0.4 | 8.7 ± 0.6 | 7.7 ± 0.5 |
| Na (mmol/L) | 149.6 ± 0.6 | 149.5 ± 0.5 | 150 ± 0.7 | 149.8 ± 0.4 |
| K (mmol/L) | 4.8 ± 0.1 | 4.8 ± 0.3 | 4.4 ± 0.1 | 4.5 ± 0.1 |
Values are presented as mean ± SEM. Sham: n = 6, sham + butaprost: n = 6, UUO: n = 8 and UUO + butaprost: n = 10.
*
P < 0.05 compared to sham;
#
P < 0.05 compared to sham + butaprost.