Table 3.
Publications Providing Overall Positive/Negative Calls for the Ames Test But No Data
| Assay version/strains | Chemical information | Results | Reference |
|---|---|---|---|
| Styrene | |||
| Plate incorporation TA98, TA100, TA1535, TA1537, TA1538 | Commercial source, highest available purity | Negative (with and without S9) | Simmon et al. (1977) |
| Preincubation Tubes were capped for volatiles TA97, TA98, TA100, TA1535, TA1537 |
Label purity: 99+% Analyzed purity: 99+% |
Negative (with and without S9) | Dunkel and Simmon (1980), Dunkel et al. (1985), Zeiger (1987), and Zeiger et al. (1988) |
| Preincubation TA98, TA100, TA1537 | No information on purity or source | Negative | Ishidate et al. (1981) |
| Plate incorporation TA98, TA100, TA1535, TA1537, TA1538 | Reagent grade pure | Negative (with and without S9) | De Flora et al. (1984) |
| Plate incorporation TA97, TA98, TA100 | Commercial source, purity 99% | Positive in TA97 and TA100 (without S9; tested between 100–1,000 μg/plate). Note that the paper has conflicting statements as to whether their results were positive or negative | Brams et al. (1987) |
| Styrene Oxide | |||
| Plate incorporation TA1535 | No information on purity or source | Positive (described as a weak positive; without S9) | McCann et al. (1975) and McCann and Ames (1976) |
| Plate incorporation TA100, TA1535 | 97% purity | Positive | Wade et al. (1978) |
| Suspension TA100, E. coli WP2uvrA | Analytical grade | Positive in both strains (without S9) | Hemminki and Falck (1979) |
| Plate incorporation G46, TA98, TA100, TA1530, TA1535, TA1538 | Commercial source, no information on purity | Positive in TA100 (without S9) | Bartsch et al. (1980) |
| Preincubation | No information on purity or source | Positive | Ishidate et al. (1981) |
| Plate incorporation TA98, TA100 | Analytical grade | Positive (without S9; tested between 30–1,000 μg/plate) | Glatt et al. (1983) |
| Plate incorporation TA98, TA100, TA1535, TA1538, TA1537 | Reagent grade pure | Positive in TA100 and TA1537 Negative in TA1535, TA1537 and TA1538 | De Flora et al. (1984) |
| Plate incorporation TA98, TA100, TA1535 | Not provided | Positive (without S9) | Khudoley et al. (1987) |
| Plate incorporation TA97, TA98, TA100 | Commercial source, no information on purity | Positive in TA97 and TA100 (without S9; tested between 600–6,000 μg/plate) | Brams et al. (1987) |
| Plate incorporation TA98, TA100, TA1535, TA1538, TA1537 | Styrene‐7,8‐glycol Reagent grade pure |
Negative (with and without S9) | De Flora et al. (1984) |