Skip to main content
. 2019 Sep 23;12:3017–3027. doi: 10.2147/IDR.S219635

Table 4.

Distribution And Corresponding Carbapenem MIC Ranges For Strains With Different Resistance Determinants

Carbapenem Resistance Mechanisms No. Of Isolates MIC Range (μg/mL)
ETP IMP MEM
Carbapenemase positive 55
 NDM-1, ESBLs, OMP loss or deficiency 10 8–256 4–64 4–128
 NDM-5, ESBLs, OMP loss or deficiency 8 16–256 8–256 4–256
 KPC-2, OMP loss or deficiency 34 4–128 1–128 1–128
 IMP-4, ESBLs, OMP deficiency 1 64 8 8
 IMP-8, ESBLs, OMP loss 1 8 8 8
 KPC-2, IMP-4, ESBLs, OMP deficiency 1 256 256 128
Carbapenemase negative 26
 AmpC, ESBLs 1 4 2 0.25
 AmpC, OMP loss 1 2 2 1
 AmpC, ESBLs, OMP loss 1 4 4 0.25
 ESBLs, OMP loss or deficiency 23 2–32 0.25–16 0.25–8