Table 4.
Carbapenem Resistance Mechanisms | No. Of Isolates | MIC Range (μg/mL) | ||
---|---|---|---|---|
ETP | IMP | MEM | ||
Carbapenemase positive | 55 | |||
NDM-1, ESBLs, OMP loss or deficiency | 10 | 8–256 | 4–64 | 4–128 |
NDM-5, ESBLs, OMP loss or deficiency | 8 | 16–256 | 8–256 | 4–256 |
KPC-2, OMP loss or deficiency | 34 | 4–128 | 1–128 | 1–128 |
IMP-4, ESBLs, OMP deficiency | 1 | 64 | 8 | 8 |
IMP-8, ESBLs, OMP loss | 1 | 8 | 8 | 8 |
KPC-2, IMP-4, ESBLs, OMP deficiency | 1 | 256 | 256 | 128 |
Carbapenemase negative | 26 | |||
AmpC, ESBLs | 1 | 4 | 2 | 0.25 |
AmpC, OMP loss | 1 | 2 | 2 | 1 |
AmpC, ESBLs, OMP loss | 1 | 4 | 4 | 0.25 |
ESBLs, OMP loss or deficiency | 23 | 2–32 | 0.25–16 | 0.25–8 |