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. 2019 May 16;248(4):396–408. doi: 10.1002/path.5271

Figure 4.

PATH-5271-FIG-0004-c

Glial scaffold and migration of GCPs in Talpid3 mutant and wild‐type cerebella. (A) P10 wild‐type and Talpid3 mutant cerebella immunostained for NeuN and Pax6. Arrows indicate ectopic NeuN+ cells in the molecular layer. The boxed region indicates enlarged area showing ectopic NeuN+ cells in the molecular layer. (B) P5, P10, and P15 cerebella immunostained for 165 kDa Nf. (C) P5, P10, and P15 cerebella labelled for GFAP. (D) Outline of P15 glial fibres immunostained for GFAP. (E) P10 cerebella immunostained for Pax6 and GFAP. Arrows indicate tangentially orientated glial fibres in the EGL. EGL, external granule layer; GFAP, glial fibrillary acidic protein; IGL, internal granule layer; ML, molecular layer; Nf, neurofilament. Scale bars: 50 μm.