Table 3.
Relationship between normal range ankle–brachial index (≥0.9) and vascular events and all‐cause mortality (N=1460)
| HR* | 95% CI | P for interaction History of vascular disease | |
|---|---|---|---|
| Myocardial infarction (n=122) | |||
| Model 1 | 1.14 | (0.97 to 1.34) | |
| Model 2 | 1.14 | (0.97 to 1.34) | |
| Model 3 | 1.09 | (0.92 to 1.28) | 0.17 |
| Stroke (n=65) | |||
| Model 1 | 1.13 | (0.91 to 1.41) | |
| Model 2 | 1.14 | (0.91 to 1.42) | |
| Model 3 | 1.10 | (0.88 to 1.38) | 0.74 |
| Vascular mortality (n=129) | |||
| Model 1 | 1.31 | (1.12 to 1.54)† | |
| Model 2 | 1.32 | (1.12 to 1.54)† | |
| Model 3 | 1.24 | (1.06 to 1.46)† | 0.43 |
| Composite of major cardiovascular events (n=237) | |||
| Model 1 | 1.17 | (1.04 to 1.31)† | |
| Model 2 | 1.17 | (1.04 to 1.31)† | |
| Model 3 | 1.13 | (1.01 to 1.27)† | 0.17 |
| All‐cause mortality (n=254) | |||
| Model 1 | 1.23 | (1.10 to 1.38)† | |
| Model 2 | 1.24 | (1.10 to 1.38)† | |
| Model 3 | 1.17 | (1.04 to 1.31)† | 0.14 |
ABI, ankle–brachial index; HR, hazard ratio.
Model 1: age + sex; Model 2: model 1 + diastolic blood pressure + BMI; model 3: model 2 + estimated GFR + non‐HDL cholesterol + smoking + pack‐years.
*
Per 0.1‐point decrease in ABI.
†
Statistically significant, P<0.05.