Table 4.
Relationship between carotid artery distensibility coefficient (10‐3 × kPa−1) and vascular events and all‐cause mortality (N=611)
| HR* | 95% CI | P for interaction History of vascular disease | |
|---|---|---|---|
| Myocardial infarction (n=106) | |||
| Model 1 | 0.99 | (0.95 to 1.03) | |
| Model 2 | 1.00 | (0.96 to 1.05) | |
| Model 3 | 0.99 | (0.95 to 1.04) | 0.68 |
| Stroke (n=51) | |||
| Model 1 | 1.09 | (1.02 to 1.16)† | |
| Model 2 | 1.13 | (1.01 to 1.16)† | |
| Model 3 | 1.07 | (1.00 to 1.15)† | 0.91 |
| Vascular mortality (n=133) | |||
| Model 1 | 1.04 | (0.99 to 1.09) | |
| Model 2 | 1.06 | (1.01 to 1.11)† | |
| Model 3 | 1.04 | (1.00 to 1.09)† | 0.76 |
| Composite of major cardiovascular events (n=195) | |||
| Model 1 | 1.01 | (0.98 to 1.04) | |
| Model 2 | 1.02 | (0.99 to 1.06) | |
| Model 3 | 1.01 | (0.98 to 1.05) | 0.51 |
| All‐cause mortality (n=244) | |||
| Model 1 | 1.04 | (1.00 to 1.07)† | |
| Model 2 | 1.05 | (1.02 to 1.09)† | |
| Model 3 | 1.04 | (1.00 to 1.07)† | 0.99 |
HR, hazard ratio.
Model 1: age + sex; Model 2: model 1 + diastolic blood pressure + BMI; Model 3: model 2 + estimated GFR + non‐HDL cholesterol + smoking + pack‐years+ end‐diastolic lumen diameter.
*
Per 10‐3 × kPa−1 decrease in distensibility coefficient.
†
Statistically significant, P<0.05.