Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Maximum registered ALT elevation in 84 patients with rheumatoid arthritis before and after starting methotrexate therapy
| Pretreatment elevation | Treatment elevation | |
|---|---|---|
| ALT > ULN, n | 20 | 84 |
| ALT > ULN but ALT < 1.5× ULN, n | 10 | 40 |
| ALT > 1.5× ULN, n | 10 | 44 |
| ALT > 1.5× ULN but ALT < 2× ULN, n | 2 | 12 |
| ALT > 2× ULN, n | 8 | 32 |
| ALT > 2× ULN but ALT < 3× ULN, n | 8 | 19 |
| ALT > 3× ULN | 0 | 13 |
ALT, alanine aminotransferase; ULN, upper limit normal
