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. 2016 Nov 28;68(12):1758–1766. doi: 10.1002/acr.22899

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© 2019, The Authors. Arthritis Care & Research published by Wiley Periodicals, Inc. on behalf of American College of Rheumatology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Time to discontinuation of biologic agent treatment in infliximab plus methotrexate (MTX) (switching from infliximab to another biologic agent within 90 days was not considered as a discontinuation), and time to biologic agent treatment start in conventional treatment and MTX responders. Conventional treatment: sulfasalazine and hydroxychloroquine plus MTX; MTX responder: nonrandomized patients who had a favorable Disease Activity Score based on 28‐joint count response to MTX after the run‐in period.